Dr. Wei-Chuan Shih, Associate Professor of Electrical & Computer Engineering

Cullen College of Engineering, Department of Mechanical Engineering

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• Areas of expertise

  • Nanobiophotonics
  • Hyperspectral imaging
  • Digital signal processing
  • Optical & ultrasonic imaging
  • Environmental Sensing: water quality, pathogen, oil spill

• Awards

  • MIT Martin Fellowship for Sustanability, MIT, 2005
  • NSF CAREER Award, NSF, 2012
  • NASA Early Career Faculty Award, NASA, 2012
  • UH Award of Excellence in Research and Scholarship, University of Houston, 2013
  • NIH Study Section Instrumental and System Development, National Institute of Health, 2011
  • NSF Regular and SBIR panels, National Science Foundation
  • UH Cullen College of Engineering Research Award, 2015

• Publications

  • Wei-Chuan Shih, “Hybrid fabrication makes better plasmonic nanostructures for SERS,” Photonics Spectra, August, 2013.
  • Wei-Chuan Shih, Kate L. Bechtel, and Michael S Feld, “Quantitative Biological Raman Spectroscopy,” in Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, Editor:  Valery V. Tuchin; Taylor & Francis (2008). 
  • Wei-Chuan Shih, Kate L Bechtel, Michael S Feld, Mark A Arnold, Gary W Small, “Introduction to spectroscopy for noninvasive glucose sensing,” in Analytical Chemistry of In Vivo Glucose Measurements; Cunningham, D.; Stenken, JA, Eds.; Wiley Chemical Analysis Series (2009). 
  • Wei-Chuan Shih, Kate L Bechtel, Michael S Feld, “ Non-invasive glucose sensing with Raman spectroscopy,” in Analytical Chemistry of In Vivo Glucose Measurements; Cunningham, D.; Stenken, JA, Eds.; Wiley Chemical Analysis Series (2009).
  • Fusheng Zhao, Jianbo Zeng, and Wei-Chuan Shih**, “In situ patterning of hierarchical nanoporous gold structures by in-plane dealloying,” (Accepted 12/7/14) (DOI: 10.1016/j.mseb.2014.12.016)).
  • Wei-Chuan Shih**, “A study of constrained regularization and its performance on non-invasive glucose sensing using Raman spectroscopy,” 2014 Journal of Innovative Optical Health Sciences (Accepted 11/24/14) (DOI: 10.1142/S1793545815500224).
  • Jianbo Zeng, Fusheng Zhao, Ming Li, Chien-Hung Li, T. Randall Lee, and Wei-Chuan Shih**, “Morphological control and plasmonic tuning of nanoporous gold nanoparticles by surface modifications,” Journal of Materials Chemistry C (First published online 11/14/2014) (DOI: 10.1039/C4TC02328E).
  • Ji Qi, Kate L Bechtel, and Wei-Chuan Shih**, “Automated image curvature assessment and correction for high-throughput Raman spectroscopy and microscopy,” Biomedical Spectroscopy and Imaging 3(4): 359-368, 2014. 
  • Md Masud Parvez Arnob, Fusheng Zhao, Jianbo Zeng, and Wei-Chuan Shih**, “Laser rapid thermal annealing enables tunable plasmonics in nanoporous gold nanoparticles,” Nanoscale 6(21), 12470-12475, 2014.
  • Narendran Sudheendran*, Ji Qi*, Eric D. Young, Alexander J. Lazar, Dina C. Lev, Raphael E. Pollock, Kirill V. Larin, Wei-Chuan Shih**, “High throughput Raman spectral imaging complements optical coherence tomography for tumor boundary detection,” Laser Physics Letters 11:105602, 2014 (*: Equal contribution). 
  • Jianbo Zeng, Ji Qi, Fuquan Bai, Jorn Yu, and Wei-Chuan Shih**, “Analysis of ethyl and methyl centralite vibrational spectra for mapping organic gunshot residue,” Analyst 139(17), 4270-4278, 2014.  

  For more publications, see CV below or click here.

• Patents

  • 62031516, Fabrication of lenses by droplet formation on a pre-heated surface  (Provisional application) Inventor: Wei-Chuan Shih and Yulung Sung; Assignee: U. Houston
  • 62004131, Nanoporous gold and silver nanoparticles and substrates for biomolecular sensing  (Provisional application) Inventor: Wei-Chuan Shih and Richard C Willson; Assignee: U. Houston
  • 61985984, Method of stamping surface-enhanced Raman spectroscopy for label-free, multiplexed, molecular sensing and imaging  (Provisional application) Inventor: Wei-Chuan Shih and Ming Li; Assignee: U. Houston
  • 61827192, Integrated thin-film optrode  (Provisional application) Inventor: John C Wolfe, Mufaddal Gheewala, Wei-Chuan Shih; Assignee: U. Houston
  • 13/796,201 Nanoporous gold nanoparticles as high-payload molecular cargos, photothermal/photodynamic therapeutic agents, and ultrahigh surface-to-volume plasmonic sensor (Non-provisional application) Inventor: Wei-Chuan Shih; Assignee: U. Houston
  • 13/741,277 “Method and system for Raman microspectroscopy  (Non-provisional patent allowance obtained) Inventors: Wei-Chuan Shih; Assignee: U. Houston
  • US8661663 Method for manufacturing a multimodal neural probe (Issued) Inventors: John C Wolfe and Wei-Chuan Shih; Assignee: U. Houston
  • US6975459 Micro-actuated adaptive diffractive composites (Issued) Inventors: G Barbastathis, SG Kim, Wei-Chuan Shih, CW Wong, YB Jeon; Assignee: MIT
  • US8124931 Method and apparatus for oil spill detection (Issued) Inventors: AB Andrews, Wei-Chuan Shih, M Clayton, OC Mullins; Assignee: Schlumberger 
  • US8362429 Method and apparatus for oil spill detection (Issued) Inventors: AB Andrews, Wei-Chuan Shih, M Clayton, OC Mullins; Assignee: Schlumberger 
  • US 8355767 Raman spectroscopy for non-invasive glucose measurements (Issued) Inventors: M. Hunter, A. Enejder, T. Scecina, M. Feld, Wei-Chuan Shih; Assignee: MIT 

• Grants and Funded Research

  • NSF EAGER: Citizen Science 2016
  • NSF CBET Nano-Biosensing 2016
  • NSF I-CORPS 2015
  • Department of Interior BSEE 2015
  • NIH R21 2014
  • GoMRI-RFPII 2012
  • NASA CAREER Award 2012
  • NSF CAREER Award 2012

  More research information in CV below and ResearchGate profile, here.

• Curriculum Vitae

  • Wei-Chuan Chin CV

• Contact information